STIL
SNU Transplantation Innovation Lab
Seoul National University
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Seoul National University Hospital  ·  Dept. of Surgery

Advancing
Transplantation
Science

Surgical innovation, artificial intelligence, and translational research — integrated to improve outcomes in kidney transplantation.

Explore Research → Publications
About the Lab

Precision transplant science — from bedside to bench and back.

The SNU Transplantation Innovation Lab aims to improve outcomes in kidney transplantation, xenotransplantation, and transplant surgery through integrated clinical research, translational science, artificial intelligence, biomarker discovery, and surgical innovation.

We bring together multicenter clinical registries, immune monitoring platforms, advanced analytics, preclinical translational models, and surgical technology to support safer living donation, longer graft survival, and more precise post-transplant care.

Kidney Transplantation Xenotransplantation AI & CDSS Biomarkers Surgical Innovation Living Donor Safety
Research

A multidisciplinary platform for transplant innovation

Clinical insight, mechanistic research, and computational methods — addressing unmet needs across the transplant continuum.

Porcine kidney NHP xenotransplantation surgical procedure
Porcine kidney NHP xenotransplantation — in-lab surgical procedure
Translational Model

Porcine-to-NHP Kidney Xenotransplantation

Our xenotransplantation program uses preclinical large-animal models to evaluate graft function, immune injury, complement activation, ischemia-reperfusion injury, and biomarker-based monitoring strategies required for responsible clinical translation.

AI Imaging Platform

Kidney Cortex AI Auto-Segmentation

AI-assisted CT segmentation quantifies total and cortical kidney volume, supports individualized living donor selection, and enables structural–functional prediction for donor safety and recipient outcomes.

Kidney cortex AI auto-segmentation CT
Bilateral kidney cortex segmentation — AI-assisted CT volumetry
KT

Kidney Transplantation Outcomes

Real-world outcome research to improve graft survival, patient safety, and center-level performance.

VOL

Living Donor Safety & Volumetry

AI-assisted volumetry, remnant kidney function prediction, and CDSS for safer living kidney donation.

IRI

Ischemia-Reperfusion Injury

Mechanistic and translational studies on early graft injury, tissue repair, and allograft protection.

XENO

Xenotransplantation

Pig-to-NHP models, immune monitoring, molecular biomarkers, and translational pathways.

AI

AI & Clinical Decision Support

Predictive modeling, dynamic risk prediction, and deployable CDSS for transplant care.

BIO

Biomarkers & Immune Monitoring

dd-cfDNA, DSA, tacrolimus, BKPyV, and longitudinal immune data for precision monitoring.

ROB

Robotic & Innovative Surgery

Robotic kidney transplantation, minimally invasive approaches, and simulation-based education.

REG

Registry Science

K-QIPS multicenter registry infrastructure for quality improvement and outcomes research.

VAS

Vascular Surgery

Complex vascular reconstruction, popliteal entrapment, portomesenteric vein interventions.

Publications

Selected Publications

39 peer-reviewed publications spanning kidney transplantation, xenotransplantation, AI, biomarkers, and clinical prediction.

2026
Clinical Front Immunol 2026

Impact of dose-adjusted tacrolimus exposure phenotype on outcomes in kidney transplantation: a large-scale multicenter cohort study

Lim D, Kim S, Han A, Ahn J, et al.

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Clinical Transplantation 2026

Deceased Organ Donation and Transplantation in LIMC: A Meeting Report

Ahn C, Stock P, Kim YH, Mannon R, et al.

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AI J Thromb Haemost 2026

Development of dynamic prediction models for venous thromboembolism recurrence and bleeding risks to guide personalized anticoagulant therapy

Jeong J, Ah YM, Han JM, Min S, et al.

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Translational Int J Mol Sci 2026

In Vitro Study on the Effects of Rhododendron mucronulatum Branch Extract, Taxifolin-3-O-Arabinopyranoside and Taxifolin on Muscle Loss and Muscle Atrophy in C2C12 Murine Skeletal Muscle Cells

Lee HS, Jang HD, Kim TH, An DH, et al.

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Clinical Kidney360 2026

Comparative Impact of Early Graft Function on Kidney Transplantation Outcomes According to Donor Types

Song J, Kang E, Jeong S, Son HE, et al.

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2025
Translational Xenotransplantation 2025

Xenograft-Derived Cell-Free Deoxyribonucleic Acid as an Early Biomarker of Rejection in Genetically Engineered Pig-to-Non-Human Primate Kidney Xenotransplantation

Han KH, Jang JY, Jung M, Hwang SA, et al.

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AI Int J Surg 2025

A preoperative nomogram and web-based clinical decision support system for predicting early renal function after living donor kidney transplantation: a retrospective multicenter cohort study

Ahn J, Kang M, Kim S, Jo EA, et al.

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Clinical Transplant Rev (Orlando) 2025

The impact of standard- versus reduced-dose tacrolimus exposure on clinical outcomes in adult kidney transplant recipients: A systematic review and meta-analysis

Udomkarnjananun S, Soliman M, Min S, An HPH, et al.

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Clinical Transpl Int 2025

Risk Prediction and Management of BKPyV-DNAemia in Kidney Transplant Recipients: A Multicenter Analysis of Immunosuppressive Strategies

Kim JM, Kwon HE, Han A, Ko Y, et al.

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Clinical BMC Nephrol 2025

Effects of the pretransplant obesity on kidney transplant outcomes in Korea: a nationwide cohort study

Cho EY, Jeon YH, Huh KH, Hwang SD, et al.

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Translational Transplant Proc 2025

Current Status of Pig-to-NHP Xenotransplantation Research in Korea

Hwang SA, Min S, Shin KC, Chee HK, et al.

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Clinical Ren Fail 2025

Persistent hyperparathyroidism after kidney transplantation in children

Park PG, Han A, Ahn YH, Min S, et al.

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Clinical Ann Surg Treat Res 2025

Outcomes of pancreas transplantation over two decades: a single-center retrospective cohort study

Shin J, Woo HY, Jo EA, Cho A, et al.

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Clinical Eur J Vasc Endovasc Surg 2025

Long Term Outcomes of Non-operative Treatment for Popliteal Artery Entrapment Syndrome: A Multicentre Study

Ahn J, Woo HY, Ahn S, Min S, et al.

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Clinical J Vasc Interv Radiol 2025

Long-Term Outcomes of Angioplasty and Stent Placement for Portomesenteric Vein Obstruction following Hepatobiliary and Pancreatic Surgery

Park JK, Han A, Hur S, Lee M, et al.

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Clinical J Korean Med Sci 2025

Strategies for Monitoring and Supporting Living Donors in Korea: An Expert Position Paper

Kang E, Woo HY, Hong SY, Lee H, et al.

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Clinical Kidney Res Clin Pract 2025

Quality of life, socioeconomic impact, and medical consideration of living kidney donors: a comprehensive survey in Korea

Kang E, Kim Y, Lee JW, Han S, et al.

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AI Ann Vasc Surg 2025

The Impact of Simulator Training of Vascular Anastomosis and Video Assessment for Surgical Residents

Woo HY, Cho A, Ko M, Shin J, et al.

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Translational Transplantation 2025

Cysteine as an Innovative Biomarker for Kidney Injury

Woo HY, An JM, Park MY, Han A, et al.

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2024
Translational Pharmaceuticals (Basel) 2024

Effects of Alnus japonica Hot Water Extract and Oregonin on Muscle Loss and Muscle Atrophy in C2C12 Murine Skeletal Muscle Cells

An DH, Lee CH, Kwon Y, Kim TH, et al.

DOI ↗
Clinical Vasc Specialist Int 2024

Long-term Patency and Complications of Endovascular and Surgical Revascularization for Takayasu Arteritis

Shin J, Cho A, Han A, Ahn S, et al.

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Clinical Int J Surg 2024

Robot-assisted kidney transplantation: a propensity score-matched cohort analysis of early experience

Kim SJJ, Kim S, Cho A, Han A, et al.

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Clinical Front Pharmacol 2024

Exploring bleeding in oral anticoagulant users: assessing incidence by indications and risk factors in the entire nationwide cohort

Jeong J, Heo KN, Lee S, Ah YM, et al.

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AI Sci Rep 2024

Perioperative glucose monitoring with continuous glucose monitors identifies risk factors for post-transplant diabetes mellitus in kidney transplant recipients

Shin J, Jo EA, Woo HY, Cho A, et al.

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Clinical Ther Adv Med Oncol 2024

Comprehensive analysis of nationwide anticancer drug-related complications in Korea: incidence, types, and cancer-specific considerations in contemporary oncology

Jeong J, Park S, Heo KN, Park SM, et al.

DOI ↗
Translational Curr Issues Mol Biol 2024

Effects of Ulmus macrocarpa Extract and Catechin 7-O-β-D-apiofuranoside on Muscle Loss and Muscle Atrophy in C2C12 Murine Skeletal Muscle Cells

Kim MS, Park S, Kwon Y, Kim T, et al.

DOI ↗
AI Int J Surg 2024

The role of artificial intelligence measured preoperative kidney volume in predicting kidney function loss in elderly kidney donors: a multicenter cohort study

Jo EA, Lee J, Moon S, Kim JS, et al.

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Translational Int J Mol Sci 2024

The Impact of Ulmus macrocarpa Extracts on a Model of Sarcopenia-Induced C57BL/6 Mice

Lee CH, Kwon Y, Park S, Kim T, et al.

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Clinical Int J Surg 2024

Optimum tacrolimus trough levels for enhanced graft survival and safety in kidney transplantation: a retrospective multicenter real-world evidence study

Han A, Jo AJ, Kwon H, Kim YH, et al.

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Clinical Sci Rep 2024

A comparative analysis of clinical outcomes between conversion to mTOR inhibitor and calcineurin inhibitor reduction in managing BK viremia among kidney transplant patients

Cho A, Park S, Han A, Ha J, et al.

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Translational Metabolites 2024

Olaris Global Panel (OGP): A Highly Accurate and Reproducible Triple Quadrupole Mass Spectrometry-Based Metabolomics Method for Clinical Biomarker Discovery

Dorrani M, Zhao J, Bekhti N, Trimigno A, et al.

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Clinical Pharmacoepidemiol Drug Saf 2024

Medication-related incidents in acute care hospitals among different age groups: An analysis of national patient safety report data

Han JM, Heo KN, Kim AJ, Lee AY, et al.

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Clinical Front Immunol 2024

The time-dependent changes in serum immunoglobulin after kidney transplantation and its association with infection

Jo EA, Min S, Jo AJ, Han A, et al.

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Clinical Eur Radiol 2024

Prediction of acute rejection in renal allografts using shear-wave dispersion slope

Kim TM, Ahn H, Cho JY, Han A, et al.

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Clinical Reg Anesth Pain Med 2024

Anterior quadratus lumborum block for analgesia after living-donor renal transplantation: a double-blinded randomized controlled trial

Kim Y, Kim JT, Yang SM, Kim WH, et al.

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Clinical Ann Lab Med 2024

Association Between Low Anti-spike Antibody Levels After the Third Dose of SARS-CoV-2 Vaccination and Hospitalization due to Symptomatic Breakthrough Infection in Kidney Transplant Recipients

Han A, Min S, Jo EA, Lee H, et al.

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2023
Clinical Korean J Transplant 2023

T cell posttransplant lymphoproliferative disorder after kidney transplantation progressing to acute liver failure: a case report

Cho JM, Kim YC, Min S, Kim TM, et al.

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Clinical Sci Rep 2023

Association of high intra-patient variability in tacrolimus exposure with calcineurin inhibitor nephrotoxicity in kidney transplantation

Kim H, Han A, Ahn S, Min SK, et al.

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Translational J Immunol Methods 2023

Application of microphysiologic system to assess neutrophil extracellular trap in xenotransplantation

Yadav SK, Park S, Lee YM, Hurh S, et al.

DOI ↗
People

Our Team

Surgeon-scientists, PhD researchers, clinical fellows, students, and research coordinators advancing transplantation science.

SNU Transplantation Innovation Lab group photo — Seoul National University Department of Surgery
Sangil Min, MD, PhD — Principal Investigator
Principal Investigator

Sangil Min, MD, PhD

Professor of Surgery, Seoul National University College of Medicine
Director, Organ Transplantation Center, Seoul National University Hospital
Head, Division of Transplantation and Vascular Surgery, SNUH

Ahram Han, MD — Sub-Investigator
Sub-Investigator

Ahram Han, MD

Associate Professor, Division of Transplantation and Vascular Surgery
Seoul National University Hospital, Seoul, Korea

Ara Cho, MD — Sub-Investigator
Sub-Investigator

Ara Cho, MD

Assistant Professor, Division of Transplantation and Vascular Surgery
Seoul National University Hospital, Seoul, Korea

Research Faculty

  • Sang Wan Kim Sang Wan Kim PhD

Graduate Researcher

  • Dong Hoon Jung Dong Hoon Jeong PhD Candidate

Clinical Fellow

  • Dong Hoon Ha MD

Research Assistants

  • 박민영 Minyoung Park
  • 곽민경 Minkyung Kwak
  • 최지연 Jiyeon Choi
  • 송창엽 Changyeop Song

Clinical Research Assistants

  • 홍혜진 Hyejin Hong
  • 권소현 Sohyun Kwon
  • 반혜빈 Hyebin Ban
Media Coverage

In the News

Selected articles and interviews on transplantation research, surgical innovation, and AI-enabled care.

메디코파마뉴스2026.04.20

[명약 인사이드][프로그랍]② '평생 친구'된 면역억제 치료

Interview on transplantation and long-term immunosuppressive therapy.

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헬스경향2026.03.26

[장기기증 특집] 삼중장벽 넘어야 생명나눔 꽃핀다

Feature article on organ donation, public trust, and system-level barriers.

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데일리안2025.12.30

서울대병원 김효수·민상일 교수, 국가연구개발 우수성과 100선 선정

National recognition for clinical validation of robotic kidney transplantation.

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중앙일보2025.09.03

서울대병원 민상일 교수를 만나다

Interview introducing kidney transplantation, surgical innovation, and clinical research.

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데일리메디2025.07.10

서울대병원 김효수·민상일·이승표 교수 'R&D 우수'

Coverage of the 2025 Health and Medical R&D Excellent Achievements.

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중앙일보2025

서울대병원 "단일공 로봇 신장이식, 아시아 최초 성공"

Media coverage of single-port robotic kidney transplantation — Asia first.

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청년의사2024.11.09

조은아 교수, 대한외과학회 '최우수 연구자상' 수상

AI-assisted kidney volume research developed with the SNUH transplant team.

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헬스조선2024.08.27

AI로 '고령 신장 기증자' 위험 예측해 이식 결정한다

AI kidney cortex volumetry for safer decision-making in older living kidney donors.

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데일리메디2024.08.07

뇌사자 공여 신장이식 성공률 높아진다

Research on cysteine-based detection of ischemic kidney injury in deceased donor kidneys.

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헬스경향2024.06.24

타크로리무스 최적 농도 확인…면역억제제 얼마나 써야 할까

Multicenter real-world study on tacrolimus trough levels and long-term transplant outcomes.

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한국일보2024.06.24

콩팥이식 후 장기 생존하려면 '면역 억제제' 농도 유지가 관건

Public-facing article on tacrolimus exposure and kidney transplant survival.

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메디칼업저버2023.11.20

돼지에서 사람에게…이종장기이식 임상시험 5년 이내 가능성

Interview on the clinical translation of xenotransplantation.

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Contact

Get in Touch

For research collaboration, fellowship opportunities, or academic inquiries, please reach out through the lab.

Emailsurgeonmsi@gmail.com
LocationSeoul National University Hospital, Seoul, Korea
DepartmentDivision of Transplantation & Vascular Surgery
InstitutionSNU College of Medicine · SNUH